How clever is this?

ZenGum • Sep 19, 2011 10:17 pm
Online gamers crack enzyme riddle
Online gamers have achieved a feat beyond the realm of Second Life or World of Warcraft: they have deciphered the structure of an enzyme of an AIDS-like virus that had thwarted scientists for a decade.

SNIP

Their target was a monomeric protease enzyme, a cutting agent in the complex molecular tailoring of retroviruses, a family that includes HIV.

Figuring out the structure of proteins is vital for understanding the causes of many diseases and developing drugs to block them.

But a microscope gives only a flat image of what to the outsider looks like a plate of one-dimensional scrunched-up spaghetti. Pharmacologists need a 3-D picture that "unfolds" the molecule and rotates it in order to reveal potential targets for drugs.

This is where Foldit comes in.

Developed in 2008 by the University of Washington, it is a video game in which gamers, divided into competing groups, compete to unfold chains of amino acids - the building blocks of proteins - using a set of online tools.

To the astonishment of the scientists, the gamers produced an accurate model of the enzyme in just three weeks.

DanaC • Sep 20, 2011 5:06 am
Wow. That really is very clever.
Griff • Sep 20, 2011 6:29 am
Truly.
footfootfoot • Sep 20, 2011 7:35 am
Not surprising at all to me and a perfect example of how the entitled view themselves as superior to those who aren't given the same opportunities as themselves®.

Hurrah for the gamers.
grynch • Sep 20, 2011 8:01 am
footfootfoot;757130 wrote:
Not surprising at all to me and a perfect example of how the entitled view themselves as superior to those who aren't given the same opportunities as themselves®.

Hurrah for the gamers.




WTF?

who are "the entitled" ... the scientists? ... do you know alot of scientists?...

ok, there are people who have had privileges, but there are also many ordinary people just slogging it out
Spexxvet • Sep 20, 2011 8:56 am
Brings to mind "Ender's Game".
Warning: spoiler alert
Clodfobble • Sep 20, 2011 8:57 am
This reminds me of reCAPTCHA. It's about time people started figuring out ways that all this wasted brain power could be put to better use. Very nice.

Of course, it's important to remember that these gamers did this for free. If this thing gets too common, they might start realizing what their skills are worth and refuse to play online puzzle games unless adequately compensated for it. :)
footfootfoot • Sep 20, 2011 9:08 am
grynch;757131 wrote:
WTF?

who are "the entitled" ... the scientists? ... do you know alot of scientists?...

ok, there are people who have had privileges, but there are also many ordinary people just slogging it out

I'm not really sure what I'm trying to say here. I have quit coffee a few days ago and I think my Lyme disease is back, but I promise you, I have a good idea in there and I will ferret it out and make it clear. And yes, I do know a fair number of docs, lawyers, and scientists, the majority of whom had enough money to go to college and get advanced degrees.

It's a long story. Just take my word for it.
grynch • Sep 20, 2011 9:20 am
footfootfoot;757143 wrote:
I'm not really sure what I'm trying to say here..


Image
Clodfobble • Sep 20, 2011 9:59 am
footfootfoot wrote:
I'm not really sure what I'm trying to say here. I have quit coffee a few days ago and I think my Lyme disease is back, but I promise you, I have a good idea in there and I will ferret it out and make it clear. And yes, I do know a fair number of docs, lawyers, and scientists, the majority of whom had enough money to go to college and get advanced degrees.

It's a long story. Just take my word for it.


Maybe what you mean is not the entitled, but the highly-formally-educated who look down on those who don't have the same degrees as they do, even though the un-degreed may be just as smart or smarter than the guy who has the piece of paper to prove it?
Lamplighter • Sep 20, 2011 10:26 am
gamers ?
footfootfoot • Sep 20, 2011 12:04 pm
Clodfobble;757158 wrote:
Maybe what you mean is not the entitled, but the highly-formally-educated who look down on those who don't have the same degrees as they do, even though the un-degreed may be just as smart or smarter than the guy who has the piece of paper to prove it?


I knew you would be able to explain this. You truly have a gift, cf.

My mind has a crush on your mind.
BigV • Sep 20, 2011 1:29 pm
footfootfoot;757183 wrote:
I knew you would be able to explain this. You truly have a gift, cf.

My mind has a crush on your mind.


get in line, buddy.
Clodfobble • Sep 20, 2011 2:18 pm
footfootfoot wrote:
I knew you would be able to explain this. You truly have a gift, cf.

My mind has a crush on your mind.


Oh! Completely random thing, but before I've forgotten it again...

The contestant on the far right totally looks like a punk rock version of you.

[YOUTUBE]hG2lV60TXmc[/YOUTUBE]
DanaC • Sep 20, 2011 2:44 pm
lol God you're right. That's Peter Serafinowiz (sp?) btw.

Excellent episode too!
Sundae • Sep 20, 2011 3:20 pm
Dana, you going to watch This Is Jinsy?
Peter Serafinowicz (I looked it up) stars in one episode. As do Tennant and Tate.

Opinion seems divided but I thought I'd at least have a look, "Has the wit to become a less malevolent League of Gentlemen".
Although part of what I love about the League is of course their malevolence...
DanaC • Sep 20, 2011 3:40 pm
Oooooh. How's this managed to pass me by? I've heard the name, but not sure where I've come across it. Having just wikid it, yes I am going to watch it.

Looks damn fine.
Lamplighter • Jun 28, 2013 9:15 pm
How would you like to be a graduate student and be the lead author on this...


Univ of Texas
June 27, 2013
Chemists Work to Desalt the Ocean for Drinking Water, One Nanoliter at a Time
By creating a small electrical field that removes salts from seawater,
chemists at The University of Texas at Austin and the University of Marburg in Germany
have introduced a new method for the desalination of seawater that consumes less energy
and is dramatically simpler than conventional techniques.

The new method requires so little energy that it can run on a store-bought battery.
<snip>

[ATTACH]44469[/ATTACH]




[YOUTUBE]x4FuObiRK7g[/YOUTUBE]
Flint • Jun 28, 2013 9:34 pm
footfootfoot;757183 wrote:

My mind has a crush on your mind.


And she's hott, too. Damn shame we didn't get a chance to party in swimsuits, but that's Texas weather for ya.
ZenGum • Jun 30, 2013 11:21 pm
http://www.sciencemag.org/content/340/6140/1545.abstract

Be sure to click the Editor's summary tab, to get it explained in regular English, but the key points are

Over 1.1 kilometers of a specially designed optical fiber that minimizes mode coupling, we achieved 400-gigabits-per-second data transmission using four angular momentum modes at a single wavelength, and 1.6 terabits per second using two OAM modes over 10 wavelengths.
Happy Monkey • Jul 2, 2013 11:34 am
Chemists Work to Desalt the Ocean for Drinking Water, One Nanoliter at a Time
...
The new method requires so little energy that it can run on a store-bought battery.
Per nanoliter?
Lamplighter • Jul 2, 2013 3:22 pm
Nanoliters today, oceans tomorrow :D

I think this is something like a gate-keeper, where the voltage
only opens and closes the gate to the flow of the (purified) liquid.

It's not like reverse osmosis where (larger amounts of)
continuous energy is needed to remove the contaminants.
BigV • Jul 2, 2013 3:48 pm
tha's nanoliters of 25% desalted water.

I can't say how promising this is, but the idea of using energy to move the water and leave the salt behind isn't new, nor difficult to scale up. Just look up, to the clouds.
glatt • Jul 2, 2013 4:02 pm
You say 25% desalted, I say 75% salted.

Yuck.
BigV • Jul 2, 2013 4:17 pm
right.

it's a proof of concept, needing dramatic increases in volume and thoroughness before it can produce drinking water (the article itself says that drinking water needs to be 99% desalted. the authors/researchers are confident [of course] that this level "can be reached".)

good on them, and good luck.
footfootfoot • Jul 2, 2013 5:08 pm
Then again there's always the old tin can under the funnel shaped plastic sheet.

How much does sun cost again? Remind me.
orthodoc • Jul 2, 2013 10:27 pm
I also vote for the tin can under the plastic sheet with a stone on top to create a funnel effect. Why can't we scale this concept up? We already know it works.

Cost of the sun, let's see ... sorry, foot, I'll have to get back to you on that complicated formula.
Lamplighter • Jul 2, 2013 10:58 pm
I've placed the order for Apple replace all your iPhones
with the tin cans and the appropriate lengths of string.
ZenGum • Jul 2, 2013 11:37 pm
Solar powered desalination stills exist and work. I forget the figures but they're big and produce only small amounts of water. Once built, they pretty much run themselves, apart from changing the water.
footfootfoot • Jul 4, 2013 9:45 pm
How about encouraging the boiling of water using vacuum tubes to heat the water? Those fuckers get hot.

Image
Lamplighter • Jul 5, 2013 12:46 am
You just re-invented the dipping duck ... perpetual motion toy.
squirell nutkin • Jul 5, 2013 6:10 am
Lamplighter;869401 wrote:
You just re-invented the dipping duck ... perpetual motion toy.


:D
Wait until you see my latest, I call it "the wheel"

;)
tw • Jul 5, 2013 9:21 am
squirell nutkin;869402 wrote:
:D
Wait until you see my latest, I call it "the wheel"
I guess we'll be seeing it once you get those problematic corners solved.
ZenGum • Jul 5, 2013 9:34 am
Only an MBA would try to cut corners like that.
tw • Jul 5, 2013 9:47 am
OMG. A disciple.
xoxoxoBruce • Jul 7, 2013 2:45 pm
Use Google's waste heat to desalinate water, or condense all that vapor coming off the nuke cooling towers.
Lamplighter • Jul 24, 2013 10:08 am
Univ of Rochester News.
7/23/13

Observation of transformation of muon neutrino to electron neutrino
is first step for experiment to explore matter-antimatter mystery.


It just takes hitting a target (underground) 185 miles away, and a lot of $

[ATTACH]44952[/ATTACH]

The current T2K collaboration consists of over 400 physicists from 59 institutions in 11 countries.
The U.S. T2K collaborating team consists of approximately 70 members
and is funded by the U.S. Department of Energy, Office of Science.

The U.S. groups have built super-conducting corrector magnets,
proton beam monitor electronics, the second neutrino horn and a
GPS time synchronization system for the T2K neutrino beamline;
and a pi-zero detector and a side muon range detector (partial detector)
in the T2K near detector complex. They are also part of the team that built,
upgraded and operates the Super-Kamiokande detector.


But what have done for me lately ?
Pete Zicato • Jul 24, 2013 12:02 pm
ZenGum;869412 wrote:
Only an MBA would try to cut corners like that.

Or upper management. :D
Happy Monkey • Jul 24, 2013 12:20 pm
They're all MBAs.