I think so. Purebred breeding cats take a lot of work to keep healthy. Part of it is the inbreeding that's ubiquitous - you can't avoid it in any purebred animals - and part seems to be that hormones, breeding, and queening are very hard on cats. When I spayed/neutered all my adults on closing the cattery they all became much easier to manage in terms of health.
The queen I have with me is able to open any lever-handled door in either direction, in spite of weighing only 7 lb. She has to jump up, balance on the handle, push it down, leap down, and push or pull the door before it re-latches. She also turns on faucets (not every day, thank goodness!) when bored. During her labors/deliveries she was always super-high maintenance - she would vocalize at every contraction, would not tolerate me leaving the room, and if she'd been able to speak English I know she would've been swearing at me! I practically had to hold her paw. But she was a fantastic mother and had gorgeous kittens.
