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If you can get your doctor to write an actual prescription for the supplement, and let the pharmacy fill it (they would basically just be taking the product off the shelves and repackaging it,) then sometimes you can get reimbursement or even get it covered from the outset if your pharmacy takes insurance. But also keep in mind what kind of copay you may have, depending on your insurance--for us, for example, most prescription copays are $40, so unless a month's supply of the supplement costs more than that, it's not worth it. But you may also be able to get your doctor to write a combination prescription to be compounded (People's Pharmacy is a good place to get prescriptions compounded,) basically having the pharmacy create a multivitamin powder that would include all the right doses of vitamins and minerals you are taking in one container. The copay for that would be considered to be for a single prescription, but it might include enough products all in one to make the cost worth it. Keep in mind though that some supplements only come in liquid vs. powdered form, etc. Oil-based supplements (like omega-3s) are unlikely to mix well with others.
One thing we do is claim all our supplements as medical deductions on our taxes. To do that, you need a letter from your doctor stating that the supplements are medically necessary to store along with your tax documents, but you wouldn't necessarily need a prescription.
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