Sell your house, or rent it out? Kids changing schools & friends?
Downside - 4 hours can be a short ride, or an eternity, depending on the urgency.
Upside - Your smart and capable of adjusting to, or rebounding from, a move that doesn't go well as planned.
I think you've already made up your mind your in a rut, and need a change... again. I hope you find what you're looking for, of course if it's change your seeking, that's pretty much a sure thing.