. . . get rid of all the stuff you (we) collect, and pare down to the minimum? Would you want to?
Think of how free you would be. If that one thing were a largish vehicle, could you fit everything in there? What constitutes one "thing." One pair of shoes? or all your shoes.
Here's a Time article:
How to Live With Just 100 Things
and here's the guy who's trying it:
The 100 Thing Challenge