Not being able to hear is extremely isolating. I saw it with my grandfather. It made him so grumpy when he'd see everyone around him laughing, and have no idea what the joke was. Then you would explain it to him, but the context would be lost. He would stop asking people to repeat themselves because it's just too much trouble and people seem put out.
Of my five senses, I'd rather lose my sense of taste first, followed by smell, and then it gets hard because touch, sight, and hearing are all critical.
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