It's rare I pick an IotD for the caption, but this is one of em. Here it is:
A model parades in front of street children, some of whom are sniffing glue, in the drug-infested 'Barrio Triste' (Sad Neighborhood) in downtown Medellin in Colombia November 7, 2005. The event was organised to entertain the children by a member of a local charity that helps children in Barrio Triste by providing food, clothes and cleaning facilities.
Reuters via Yahoo news.