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-   -   Future Medical Technology (http://cellar.org/showthread.php?t=28918)

xoxoxoBruce 04-20-2013 05:15 PM

Future Medical Technology
 
There's a lot of new things in the pipeline. Like always, it's a matter of when.
Quote:

Brain Cells From Urine
In a sentence we won’t get to use often, researchers have turned pee into human brain cells. At the Guangzhou Institute of Biomedicine and Health in China, biologists have taken waste cells from urine and modified them with the use of retroviruses to create progenitor cells, which the body uses as the building blocks for brain cells. The most valuable benefit to this method is that the new neurons created haven’t caused tumors in any of the mice used for testing.
Maybe this is the answer, for parents who feel their children are pissing away their education. :haha:

sexobon 04-20-2013 10:49 PM

Pee brains.

footfootfoot 04-20-2013 11:10 PM

Retroviruses? That's so 70s.

ZenGum 04-21-2013 06:56 AM

Neural cells are what we would need to cure spinal injuries. This is damn cool.

We've also recently made mouse kidneys from mouse skin cells.

footfootfoot 04-21-2013 09:49 PM

Well, that great news for mice, does their insurance cover that, though?

glatt 04-22-2013 07:48 AM

Republicans would mock research with mouse pee. So China is doing it, and getting terrific results. It won't be long before we're pirating China's innovations.

infinite monkey 04-22-2013 07:55 AM

Quote:

Originally Posted by footfootfoot (Post 861937)
Well, that great news for mice, does their insurance cover that, though?

Yeah, what if they're piss poor?

footfootfoot 04-22-2013 08:51 AM

You gotta be kidneying me.

infinite monkey 04-22-2013 09:07 AM

Nah, I'm a liver, not a fighter.

jimhelm 04-22-2013 01:31 PM

Quote:

Originally Posted by glatt (Post 861971)
Republicans would mock research with mouse pee. So China is doing it, and getting terrific results. It won't be long before we're pirating China's innovations.

it's a hoax. remember, they warned us in grade school.



Me Chinee, Me play joke. Me put Pee pee in your.....brain.

footfootfoot 04-22-2013 02:06 PM

Chinese
Japanese
Dirty knees
look at these

xoxoxoBruce 04-22-2013 04:59 PM

Worm Therapy
 
Worm therapy... shudder

Quote:

A month later, Turk saw an ad on the news seeking multiple sclerosis patients to try out an unusual new treatment at the University of Wisconsin, in his hometown of Madison. Patients were being asked to infect themselves with live pig whipworm eggs to see if the parasites alleviated any of their symptoms or slowed the spread of telltale brain and spine lesions.
Quote:

Six years later, the group published the result of two preliminary trials in humans. In one, involving 54 ulcerative colitis patients, 43% of those given pig whipworm eggs improved, compared with only 17% who received placebos.
In a second trial 29 patients with Crohn’s disease took whipworm eggs every three weeks. By the end of 24 weeks, 79% had reduced disease activity and 72% had gone into remission.
Quote:

Patients must re-infect themselves every few weeks but do not risk a chronic infection potentially spiralling out of control, or of accidentally infecting family members. “Pig whipworm is very kosher,” Weinstock says.
Quote:

Gastroenterologist John Croese, at the Prince Charles Hospital in Brisbane, is inoculating 12 coeliac disease patients, who suffer from gluten intolerance, with hookworms. Gluten is slowly introduced into their diets to see if the hookworms will suppress the disease’s inflammatory response.
The theory is, as we've cleaned up our act, you know, sterilized our environment, over the past few hundred years. We've mostly eliminated these parasites, and that changed the zoo in our guts, which led to other problems.

orthodoc 04-22-2013 06:16 PM

Whipworms! Hookworms! Agghh .... *shudder*

I'll pass, thanks. I just can't see that we need parasites to balance our intestinal flora. Bleargh.

xoxoxoBruce 04-22-2013 07:33 PM

I agree, yuukkk.
But the MS reduction of brain and spine lesions intrigued me.

glatt 04-23-2013 07:26 AM

The 72% remission in Crohn's is an amazing number. That can't all be attributed to the worm, right? Does Crohn's go into remission on its own all the time? How did the control do?

Edit: Here's an article talking about a pig whipworm Crohn's study that appears to be happening now.

footfootfoot 04-23-2013 08:28 AM

That makes sense to me. Aren't there a number of parasites and insects that inject some sort of enzyme or something that shuts off the host's immune response in order to create a more welcoming nest for itself?

glatt 04-23-2013 08:35 AM

Apparently the good (or bad?) thing about the pig whip worm is that since humans aren't its normal host, it can't survive for more than a couple weeks in our guts, so you gave to keep re-ingesting them. I guess that's good because you don't want them taking your body over, but it would be nice if you could get the treatment and then be done with it. But it looks like you need to be doing it forever.

Now might be a good time to get into the pig whip worm production business. You just have to figure out how to wash the eggs out of the manure and sterilize them efficiently.

Clodfobble 04-23-2013 09:35 AM

This has been floating around for awhile as a do-it-yourself non-FDA-sanctioned treatment for a number of autoimmune diseases. I know parents who buy them online and give them to their kids. I'm glad to see they might be able to get a prescription for it someday.

Happy Monkey 04-23-2013 06:20 PM

Quote:

Originally Posted by glatt (Post 862142)
Apparently the good (or bad?) thing about the pig whip worm is that since humans aren't its normal host, it can't survive for more than a couple weeks in our guts, so you gave to keep re-ingesting them. I guess that's good because you don't want them taking your body over, but it would be nice if you could get the treatment and then be done with it.

There's a chance that if this treatment is frequently used, we'll get a human-tolerant variant at some point.

Whether that will be good or bad is another question.

ZenGum 04-23-2013 06:45 PM

Hmmmm, good point. Life ..... finds a way... Put a gazillion pig whip worms into human guts, one of those worms is going to suddenly find it fits in.

footfootfoot 04-23-2013 09:03 PM

Quote:

Originally Posted by Happy Monkey (Post 862280)
There's a chance that if this treatment is frequently used, we'll get a human-tolerant variant at some point.

Whether that will be good or bad is another question.

It all depends on whether Monsanto gets involved.

Lamplighter 12-12-2013 10:12 AM

Bill and Melinda Gates have been spending enormous sums of $ fighting malaria worldwide.
But...

There are reports of drug-resistant strains of malaria appearing in some villages
where treatment efforts had been sufficient to reduce the incidence of the disease.

But also, with some success in treatment also comes complacency.
Funding for the bed-nets has dropped so primary prevention will drop too.

Were I to be one to approve mega-funding for malaria, I'd look to the geneticists
who are developing the "one-size-fits-all" influenza vaccine containing
all of the various mutant genes that are in the flu genome.

In any case, I hope but doubt malaria will be "conquered" in the lifetime of any current generation. :(

footfootfoot 12-12-2013 12:06 PM

At the risk of sounding like a eugenicist, diseases play an important part in keeping a species strong. We are essentially breeding drug resistant bugs while making our own species generally weaker by allowing members who would otherwise have died to pass on their less vigorous genes.


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