The Cellar - I should have kept my deviated septum

The Cellar (http://cellar.org/index.php)

- Health (http://cellar.org/forumdisplay.php?f=33)

- - I should have kept my deviated septum (http://cellar.org/showthread.php?t=27981)

kinda gross. but, GAWD, doesn't it feel better now?

Quote:

Originally Posted by Clodfobble (Post 828615)

I know, right? And the first thing I had to do was take a picture of it.

notacompetition notacompetition notacompetition notacompetition

Quote:

Originally Posted by limey (Post 828622)

Haggis!

Isn't it a little small for that?

Wow. That's actually cool.

You had no idea that was in there? And they couldn't tell you? "Oh, by the way, if a shrinky dink comes out of your nose, don't be alarmed."

Maybe if you put it in water it'll expand into a six inch shark in 24 hours?

Quote:

Originally Posted by glatt

You had no idea that was in there?

None whatsoever. My nose still feels swollen almost completely shut even now, but never did I have a sensation of something moving about.

You could try cured salted pork plugs. :eek:

Quote:

Originally Posted by xoxoxoBruce (Post 828717)

You could try cured salted pork plugs. :eek:

Are you kidding me??? :eyebrow:

Quote:

Methods: We present a unique case report of a 4-year-old child with known Glanzmann thrombasthenia and two separate episodes of life-threatening epistaxis that were treated successfully by nasal packing with strips of cured pork because of special circumstances.
Results: Cured salted pork crafted as a nasal tampon and packed within the nasal vaults successfully stopped nasal hemorrhage promptly, effectively, and without sequelae. In both applications, the patient had complete cessation of nasal bleeding within 24 hours, and was discharged within 72 hours after treatment.

WTF "special circumstances" lead you to shove pork tampons up a four-year-old's schnoz???

Probably something like, "oh shit, the hemophiliac boy is bleeding out again, we're in the middle of nowhere on our way to market with the cured saltpork, and he's already saturated all our handkerchiefs and rags."

As a veteran nosebleeder even before all this, I can confirm that when it starts flowing, it gets very bloody very fast. The miracle solution I started using in recent years was to douse my tissue in liquid vitamin K before cramming it up there, which stops it immediately (and doesn't waste good bacon either.) I mentioned this to the doctor and even brought the bottle the third time we went back to the ER so she could put in on the nose tampons she was ging to use, but she wasn't comfortable using it just on my say so.

Quote:

Originally Posted by Clodfobble (Post 828782)

Twice???

Quote:

Originally Posted by Undertoad

When you eat vitamin K, it helps build the proteins in your blood that are needed for coagulation. That doesn't happen when you put it up your nose, so why does it work well?

My understanding is that Vitamin K is used in about 7 different ways at different parts of the coagulation cycle, and that most of these processes happen (or are available to happen) rather instantaneously within all cells, not at a central organ or over a long period of time. Wiki goes over my head, but seems to be saying this:

Quote:

The function of vitamin K in the cell is to convert glutamate in proteins to gamma-carboxyglutamate (Gla).

Within the cell, vitamin K undergoes electron reduction to a reduced form called vitamin K hydroquinone by the enzyme vitamin K epoxide reductase (VKOR).[70] Another enzyme then oxidizes vitamin K hydroquinone to allow carboxylation of Glu to Gla; this enzyme is called the gamma-glutamyl carboxylase[71][72] or the vitamin K-dependent carboxylase. The carboxylation reaction will proceed only if the carboxylase enzyme is able to oxidize vitamin K hydroquinone to vitamin K epoxide at the same time; the carboxylation and epoxidation reactions are said to be coupled. Vitamin K epoxide is then reconverted to vitamin K by VKOR. The reduction and subsequent reoxidation of vitamin K coupled with carboxylation of Glu is called the vitamin K cycle.[73] Humans are rarely deficient in vitamin K1 because, in part, vitamin K 1 is continuously recycled in cells.[74] Avotresante (talk) 22:17, 7 August 2012 (UTC) Warfarin and other coumarin drugs block the action of the VKOR.[75] This results in decreased concentrations of vitamin K and vitamin K hydroquinone in the tissues, such that the carboxylation reaction catalyzed by the glutamyl carboxylase is inefficient. This results in the production of clotting factors with inadequate Gla. Without Gla on the amino termini of these factors, they no longer bind stably to the blood vessel endothelium and cannot activate clotting to allow formation of a clot during tissue injury.

By putting it on my opened/bleeding vessels, I have put it in my bloodstream, faster than I would have if I'd eaten it. The only question is, how fast can the cycle from glutamate to Gla operate? I will say that I have to leave the nose plug in for about 5-7 minutes for the bleeding to stop, but it only takes the one--without the vitamin K in there, it just soaks the noseplug in about 30 seconds and keeps right on going. I've had gushing nosebleeds that last 45 minutes, no matter how much pressure I put on them.

That's good to know, i must get some, thanks

Eeeew, that's yucky.

But fascinating! Thanks C.

Makes sense I s'pose. Speed and cocaine work differently depending on what part of the body absorbs them.